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There are a number of situations where it has been suggested that cloning technology could be applied to make a "copy" of another human being. RELATED >>

  • Parents might wish to "replace" an aborted fetus, dead baby or child killed in an accident. A grieving woman whose husband and daughter have been killed in the same car crash, may wish to use the DNA from one of her daughter's cells and insert it into an egg supplied by another woman. The child born would be a clone of her dead daughter. However, the mother would not be "getting back" the same child that had died.

  • In the case of a child dying of kidney failure and where neither parent can donate a compatible organ, parents might wish to have a further sibling, produced by cloning, to be a compatible organ donor, as this would avoid a rejection reaction. One of this child's kidneys might then be transplanted to save the life of their older sibling.

  • An individual might seek to use cloning technology in an attempt, as that individual might see it, to cheat death.

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There are moral arguments to support the claim that human dignity forbids the use of human beings only as a "means", holding that they are to be treated as an "end" in their own right. What implications do these considerations have for the ethics of human reproductive cloning? There are many general questions about intervention and reproductive technology, which are not unique to cloning. For example, what limits are there on the role of prior choice of characteristics in offspring, where this is scientifically made possible. These presumably apply equally to cloning and include the obvious need for safety issues to be addressed fully. RELATED >>
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A potential application of human reproductive cloning by nuclear replacement might be to assist human reproduction. A lesbian couple might wish to have a child. Here the cell nucleus from one woman could be inserted into an enucleated egg from the other. The resulting embryo might then be implanted in the uterus of the woman who donated the egg. Another scenario might be where both individuals of a couple are infertile or where the prospective father has non-functional sperm. In this case, cloning one member of the couple to create offspring might be envisaged. Would the use of nuclear replacement techniques be beyond the limit of what is ethically acceptable to resolve a couple's infertility problem?
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Irrespective of whether it would be desirable, there is considerable doubt about whether it would even be possible to clone humans using the techniques used to produce Dolly the sheep. The nuclear replacement technology used to produce Dolly is still in its early stages. We do not yet know whether the work which created Dolly is repeatable in animals, nor is it known whether it can be replicated in humans. We should bear in mind that Dolly was the only normal lamb born from 276 similar attempts. Only 29 resulted in implantable embryos, all of which, except the one leading to Dolly, resulted in defective pregnancies or grossly malformed births.
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Francis Collins

 
Science

HGProject
By the 1980s the base sequence of a large number of genes had been determined through many individual contributions, providing much crucial information to biology and medicine.

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Prevention
The management of genetic disease can be divided into prevention and treatment.

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